Sclerotherapy is the most common and effective treatment for spider veins of the legs and for certain varicose veins. During the treatment, a sclerosing solution is injected into the vein through a tiny needle, which irritates the lining of the vessel. This leads to a healing process and the vein gradually fades. Some veins disappear completely while others fade significantly. Several sclerotherapy treatments may be required to achieve optimal results. Discomfort is minimal and you may resume regular activities immediately following a treatment. Vigorous exercise is to be avoided for 1 to 2 days. Support hose or a snug wrapping to the treated area may be recommended.